Arsenal have a great run of fixtures after the international break with home games against Palace, Villa, Watford and Newcastle over the next six matches. Chelsea also have a great run with the next two against newly promoted opposition. 

Southampton have the best fixtures from a defensive standpoint with games against Burnley, Watford and Norwich in three of the next five so Livramento could be a great pick. Chelsea's defence also looks worthy of investment looking at their next four opponents - Brentford, Norwich, Newcastle and Burnley. 

Man. Utd are at the bottom of the fixture ticker for the next six gameweeks so managers with the likes of Shaw, Greenwood and Ronaldo in their teams should take note. West Ham also have a difficult run and managers will soon have to make a decision on the likes of Antonio and Benrahma.